Best AdSense Niche 2022 & Highest CPC Keywords List for USA

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Best AdSense Niche 2022 & Highest CPC Keywords List for USA. Making money online can be quite hard, especially if you want to monetize your blog solely via ads. To be a successful AdSense publisher, you need a lot of traffic to engage with the ads displayed on your site.

Best AdSense Niche 2022 and Highest CPC Keywords list for USA The AdSense CPC you get paid for will depend on the topics you write about. In the world of blogging, you can either write articles that will compete for clicks that will spend a few cents or be strategic and write content that will deliver the big bucks.

Here are the top 10 highest-paid AdSense keywords for 2022 (by industry/niche)

1. Insurance $61 CPC
2. Gas/Electricity $58 CPC
3. Loans $50 CPC
4. Mortgage $46 CPC
5. Attorney $48 CPC
6. Lawyer $42 CPC
7. Donate $42 CPC
8. Conference Call $42 CPC
9. Degree $40 CPC
10. Credit $38 CPC

Which AdSense did ads pay the most?

Highest CPC Keywords and Best AdSense Niches In addition to picking the best niche for AdSense, you also have options for which ad type to show. The possibilities are: 1) text & display, 2) matched content, 3) in-feed, and 4) in an article.

To set up Auto ads on your site, follow these steps:

1. Sign in to your AdSense account.
2. In the left navigation panel, click My ads.
3. Click Auto ads.
4. On the “Choose your global settings” page, use the controls to select the ad formats you want to show.
5. Leave Automatically get new formats selected if you want AdSense to automatically add new ad formats to your global settings as they become available.
6. Click Save.
7. On the “Place code on your page” page, click Copy code.
8. Paste the ad code between the <head> and </head> tags of each page where you want to show Auto ads.

Bonus Keyword Industries/Niches

Here are other high-paying keywords that you can target in your blog posts:

1. Treatment $41 CPC
2. Software $39 CPC
3. Classes $36 CPC
4. Recovery $34 CPC
5. Trading $33 CPC
6. Rehab $33 CPC
7. Hosting $31 CPC
8. Transfer $29 CPC
9. Cord Blood $27 CPC
10. Claim $25 CPC

Which exact keywords pay the most CPC on AdSense?

SEMrush did an excellent study of some of the best keywords by country. Best AdSense Niche and Highest CPC Keywords (2022)

If you are looking for exact top-paying keywords such as mesothelioma, which pays $1000+ per click, you can check out the list of 1M+ AdSense keywords by Grep Words. For instance, they reported the ultimate top-paying keyword, “mesothelioma survival rates,” at $1006.56 per click.

Mesothelioma Keywords sorted by CPC.

Mesothelioma is a type of cancer that lines the lungs, stomach, heart, and other organs and, unfortunately, can’t be cured. Nevertheless, treatment can help reduce the pain. People that contracted mesothelioma did so at their jobs, so that is why you see searches like “mesothelioma attorneys,” “mesothelioma law firms,” and “mesothelioma compensation.”

Top Paying Keywords for the Lawyer Niche

Being a lawyer must be excellent. You get to dress in a suit (which I love), and you also get to afford to spend exorbitant amounts of money on website traffic. Not too shabby.

Doctors keywords CPC AdSense

In this list, you will find a mix of people looking for Physicians and people looking for a Ph.D. program.

Best Attorney AdSense Keywords

I thought attorneys and lawyers were the same. Guess I was wrong. Best AdSense Niche and Highest CPC Keywords 2022

Here are some other keywords about attorneys:

Educational keywords

Bitcoin CPC AdSense KWs

I threw this one in because the crypto space is so hot. These keywords are not the highest paying on my article roundup, but I expect their cost per click to rise in the coming years.

Top Paying Insurance-Related AdSense Keywords

Best AdSense Niche and Highest CPC Keywords 2022 The insurance companies indeed make a killing from those outrageous premiums they charge us. Otherwise, how could they afford all those TV commercials and the crazy spending on AdWords? If you are in the insurance blogging space, kudos to you. You’ve picked a winner.

Best Digital Marketing/SEO AdSense Keywords

If you are a regular reader of my blog, you are most likely interested in all things online marketing / SEO, so this list is for you:

Keywords to target if you are in the ‘software for fitness’ niche

Bonus #1: Target these countries if you want to earn 10x more:

Highest CPC Keywords and Best AdSense Niches 2022 Aiming for the right countries can really skyrocket your AdSense earnings. Here are the top 10 countries to target:

Bonus #2: Unlock even more revenue by blocking low CPC ads

As a publisher, you have much control over which Ad Categories you want to show on your site.

If you are trying to raise the CPC, RPM, or CPM of your AdSense ads, I suggest you look at your ad performance and start blocking categories that are not paying well.

Also Read: Best Mesothelioma and Asbestos Law Firms in USA

1. Go to AdSense and on the left-hand column, click on “Blocking Controls > Content> All Sites.”
2. Click on “General Categories.”
3. Sort by % Earnings (Ascending).
4. You can see which ads take a good amount of impressions but generate relatively low earnings.

Impressions but generating relatively low earnings.

Best AdSense Niche and Highest CPC Keywords 2022 For instance, the “Hobbies Games & Leisure” category is taking 4% of impressions yet just making 0.7% of your revenue. You can try and block it and see if your performance improves.

A word of caution: Don’t block too many categories (or ad networks); you will significantly reduce the bid competition and drive your revenue down.

Pro tip: Run Optimization Experiments

You can always run an Experiment (found under Optimization > Experiments) and see if blocking your ads yields more revenue.

For instance, I am running the experiment of blocking specific categories. As you can see below, I have already started to see some good results (unfortunately, AdSense policies prevent me from sharing the exact numbers).

Bonus #3: Steal your competitor’s lunch (aka. find which keywords are driving the most revenue to them)

What if you could view which keywords get your competition the most clicks and revenue?

I’ll show you how I do it.

1. Find an authority site in your niche. (For the sake of example in online marketing, I will use my site)
2. Type that site on the search bar in SEMRush
3. Scroll to “Top Organic Keywords” and click “See Full Report.”
4. On that report, sort by CPC.
5. Voilá, you have a list of potential keywords that you can now use.
6. Rinse and repeat with other sites that you admire.

Bonus #4: Find more high-paying keywords using the Search Console

Best AdSense Niche and Highest CPC Keywords 2022 Did you know that it already provides you with the keywords you rank for? What if you could optimize your existing blog posts to target even better keywords?

Instead of spending tons of hours writing a thorough post, you could use updating an old one and picking juicier keywords. Here’s how.

1. Install the Keywords Everywhere Chrome Extension
2. Head to the Search Analytics under the Webmasters Tools
3. Choose your website
4. Be sure to check the Clicks, Impressions, CTR, and Position boxes at the top
5. Filter by any specific page that you want keywords to show for.

6. Since you installed the Keywords Everywhere tool, you will see an additional 3 columns on your list: Monthly Volume, CPC, and Competition.

As you can see, this last trick will yield keywords that might not apply to your blog post. The “mesothelioma lawyer directory” does not apply to this specific post, so I will just ignore it.


I hope you found this list of high-cost-per-click keywords proper. I also hope you liked the strategy to find keywords from which your competitors are getting money. If you want additional tools to find keywords, head to my SEO tools list.

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